I just ordered my first kindle, and it comes tomorrow! I am very excited!
I am not going to use it really to read best sellers, but for my school books. I have 5,901 pages of assigned reading so far this semester, and much of it is avalible on the kindle. More importantly, though - almost 1,000 of those pages are on PDF's, so either I could print that all out (I can print 800 pages free with my tuition, but its not enough and a total waste of paper) or I can email it to the kindle DX I just bought and read them on there, plus that way I have them all in one place for easy reference.
I will let you know what I think when it comes, but I am pretty sure its gonna be wonderful!