I think it is all up to the individual, if you don't enjoy something anymore, it's not worth it to push the issue hoping for different results.
I hope that I never get tired of trying different cigars. I get a little rush when I start looking at new cigars, thinking of how they will taste, if it will be the next one to get an honored box spot in the humidor.
Scott, If you are happy with smoking Padron's and nothing else, well brother, I am happy for you and hope everyone that you light is just wonderful and satisfying, cuz that's what all of this is about anyway. Satisfaction through friends, fellowship, food, drink, and a nice little tube of tobacco!!