Regarding the crushability of the tablets...some companies (like the one I work for) are working on technology that would eliminate the ability to crush the tablets to get more drug into their systems faster. Additionally, this technology shows increased resistance to alcohol, as well. I wish I could tell you more about them, but things are on the horizon that will be used in conjunction with medications like this.
That being said, I hate working with these active ingredients. First, there is the two person rule whenever you have them out (as they are all controlled substances) and then there is the increased attention to getting dosed wth it. If the material is a fine and light, then we wear masks, so as not to get dosed by inhalation. I got dosed with a controlled substance one time like that (the active ingredient in an anti anxiety med) and slept for like 13 hours. LOL VERY relaxed.
I haven't taken basically any meds like these, thankfully, so the only experience I can give is what I know about through the media and work.