In the case of my tank, the center brace is a somewhat of a support but I stil managed to build it with ballroom dancing space. Both sets of doors on both sides swing completely open with nothing to obstruct.
My filtration is more like what your wet dry will look than the one I did for my customer. Mine is 12 yrs old and I did it much simpler than, before I got into the complicated plumbing. I have been updating it here and there through the years but never splurged on a new custom built wet dry as I did for customers.
To give you an idea, that is a 72" long furniture and that wet dry is 36" long.
Note the tape and arrow BC-Axeman was referring to.